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Updated: Aug 11, 2026

The Trier Social Stress Test Protocol for Inducing Psychological Stress
Published on: October 19, 2011
How does the subjective experience of stress relate to the breakdown of the human immune system
1Human Physiology Class, University of Wisconsin, Stevens Point 54481.
Abstract:
Life and health in a modern industrial society requires a continuous adaptation of the body to a variety of extraneous influences. Adequate adaptation is brought about by a balanced interaction of the nervous system, the endocrine organs, and the immunocompetent tissues. Deviation of such balanced response leads to "stress" in the sense of Hans Selye and may cause pathological reactions, i.e. disease. The present article reviews the current knowledge of functions and disturbances in the field of psychoneuroimmunology and endocrinology.
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