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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

IL-17 contributes to CD4-mediated graft-versus-host disease

Lucy W Kappel1, Gabrielle L Goldberg, Christopher G King

  • 1Department of Medicine and Immunology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

Blood
|October 22, 2008
PubMed
Summary

Interleukin-17 (IL-17) plays a role in the early stages of graft-versus-host disease (GVHD) by promoting inflammatory cytokines. However, IL-17 is not essential for overall GVHD mortality or graft-versus-tumor (GVT) activity.

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