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Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
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Related Experiment Video

Updated: Jun 28, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

CT protocol for acute stroke: tips and tricks for general radiologists.

Enrique Marco de Lucas1, Elena Sánchez, Agustín Gutiérrez

  • 1Department of Diagnostic Radiology, Hospital Universitario Marqués de Valdecilla, Cantabria, Spain. radmle@humv.es

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|October 22, 2008
PubMed
Summary

Advanced CT imaging, including perfusion CT and CT angiography, is crucial for diagnosing acute stroke. This comprehensive approach aids radiologists in identifying ischemic tissue and guiding treatment decisions effectively.

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Published on: January 15, 2017

Area of Science:

  • Radiology
  • Neurology
  • Medical Imaging

Background:

  • Acute stroke management is a common task for on-call radiologists.
  • Imaging is essential for current thrombolysis guidelines.
  • Nonenhanced CT is necessary for detecting early ischemic signs or hemorrhage.

Purpose of the Study:

  • To highlight the importance of modern CT techniques in acute stroke diagnosis.
  • To explain the role of perfusion CT and CT angiography in stroke assessment.
  • To emphasize the utility of a complete CT protocol for effective stroke management.

Main Methods:

  • Utilizing nonenhanced computed tomography (CT) to identify early ischemic changes and hemorrhage.
  • Employing perfusion CT to delineate ischemic penumbra (increased mean transit time, decreased cerebral blood flow, normal/increased cerebral blood volume) and infarcted tissue (decreased cerebral blood flow, decreased cerebral blood volume).
  • Performing CT angiography to locate occlusions, assess collateral flow, and characterize carotid atherosclerosis.

Main Results:

  • Perfusion CT effectively differentiates between ischemic penumbra and infarcted tissue based on specific hemodynamic parameters.
  • CT angiography accurately identifies the site of vascular occlusion and evaluates collateral circulation.
  • A complete CT examination (nonenhanced, perfusion, and angiography) provides a comprehensive stroke assessment.

Conclusions:

  • A complete CT study including nonenhanced CT, perfusion CT, and CT angiography is vital for acute stroke diagnosis.
  • These advanced CT techniques enable rapid and accurate assessment of ischemic tissue and vascular status.
  • Standardized protocols facilitate the use of comprehensive CT by general radiologists, improving stroke diagnosis and patient care.