Jove
Visualize
Contact Us

Related Concept Videos

Altered States of Awareness01:06

Altered States of Awareness

Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain that...
Hepatic Encephalopathy01:29

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Cognitivism01:17

Cognitivism

Cognitive psychology emerged as a significant field in the mid-20th century. It focused on understanding humans' internal mental processes. This approach emphasizes how people perceive, remember, think, and solve problems—elements critical to human cognition.
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process information is...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Barriers to Aging in Place for Rural, Institutionalized Older Adults: A Qualitative Exploration.

Clinical gerontologist·2020
Same author

An escape into fiction.

Science (New York, N.Y.)·2019
Same author

Noninvasive Determination of Blood Pressure by Heart Sound Analysis Compared With Intra-Arterial Monitoring in Critically Ill Children-A Pilot Study of a Novel Approach.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·2019
Same author

Family-centered care in the pediatric intensive care unit.

Pediatric clinics of North America·2013
Same author

Let's reflect: what is the point?

The British journal of general practice : the journal of the Royal College of General Practitioners·2011
Same author

Saplings into oaks.

The British journal of general practice : the journal of the Royal College of General Practitioners·2009
Same journal

Effect of Preferred Language on Pediatric Rapid Response Activation and Subsequent Intensive Care Utilization.

Clinical pediatrics·2026
Same journal

Documented Caregiver Report of Wheezing at Home is Associated With Decreased Length of Pediatric Asthma Hospitalizations.

Clinical pediatrics·2026
Same journal

The Rash That Will Not Go Away.

Clinical pediatrics·2026
Same journal

Virtual Reality Education for Hospitalized Pediatric Patients Improves Intrinsic Motivation: A Prospective, Randomized Crossover Study.

Clinical pediatrics·2026
Same journal

Pediatric Invasive Group A Streptococcus Characteristics Before, During, and After COVID-19.

Clinical pediatrics·2026
Same journal

Lichen Sclerosus: A Common but Often Overlooked Condition in Pediatric Patients.

Clinical pediatrics·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 28, 2026

Assessment and Communication for People with Disorders of Consciousness
07:37

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

Integrative basic sciences: change in mental status.

Erika Crane1, Jeff Clark

  • 1Children's Hospital of Michigan, Detroit, MI 48201, USA. ecrane@med.wayne.edu

Clinical Pediatrics
|October 22, 2008
PubMed
Summary
This summary is machine-generated.

This case highlights how understanding basic physiology, like acid-base balance, aids in diagnosing altered mental status. It shows ethanol toxicity as a cause, emphasizing the link between basic science and clinical practice.

More Related Videos

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

Related Experiment Videos

Last Updated: Jun 28, 2026

Assessment and Communication for People with Disorders of Consciousness
07:37

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

Area of Science:

  • Medical Education
  • Clinical Physiology
  • Toxicology

Background:

  • Integrates basic science into clinical teaching.
  • Focuses on altered mental status (AMS) and its physiological underpinnings.
  • Utilizes anatomy and physiology to guide differential diagnosis.

Observation:

  • A 13-year-old boy presented with unresponsiveness and altered mental status.
  • Physical examination was largely unremarkable.
  • Initial laboratory studies included arterial blood gas, electrolytes, and serum osmolality.

Findings:

  • Physiologic principles of acid-base balance, anion gap, and osmolar gap were applied.
  • Laboratory results, interpreted through physiological concepts, led to a focused differential diagnosis.
  • Subsequent investigation confirmed ethanol toxicity as the cause of AMS.

Implications:

  • Demonstrates the practical application of basic science (anatomy, physiology) in clinical decision-making.
  • Highlights the utility of fundamental laboratory studies in diagnosing AMS.
  • Reinforces the importance of electrolyte and acid-base balance in clinical assessment.