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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
Corynebacterium-associated skin infections
Géraldine Blaise1, Arjen F Nikkels, Trihn Hermanns-Lê
1Department of Dermatopathology, University Hospital of Liège, Liège, Belgium.
International Journal of Dermatology
|October 22, 2008
Summary
Pitted keratolysis, a bacterial infection of the feet, primarily affects young males who wear protective shoes. Key symptoms include hyperhidrosis, odor, and pain, often linked to moist environments.
Area of Science:
- Dermatology
- Microbiology
Background:
- Pitted keratolysis is a plantar infection caused by Corynebacterium spp.
- It affects the stratum corneum, the outermost layer of skin on the feet.
Purpose of the Study:
- To investigate demographic features of patients with pitted keratolysis.
- To review Corynebacterium-associated infections like pitted keratolysis, erythrasma, and trichobacteriosis.
Main Methods:
- A 2-year prospective survey at two centers.
- Assessed demographics, infection sites, symptoms, shoe habits, and associated skin conditions in 53 patients.
Main Results:
- The average patient age was 24.9 years, with a male to female ratio of 7.8:1.
- Most patients (92.4%) had infections on both soles, often in pressure-bearing areas.
- Hyperhidrosis (68%), unpleasant odor (66%), and pain (47%) were common complaints, with 96.2% wearing occlusive shoes.
Conclusions:
- Pitted keratolysis predominantly affects young males in professions requiring protective footwear.
- The condition thrives in moist, warm environments created by occlusive shoes.
- Hyperhidrosis, odor, and pain are the primary clinical manifestations.
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