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Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...

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Acute Coronary Syndrome I: Introduction

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Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

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[Left main coronary artery stenosis].

Imad Sheiban¹, Giuseppe G L Biondi-Zoccai, Claudio Moretti

¹Divisione di Cardiologia, Università degli Studi, Ospedale San Giovanni Battista Molinette, Torino. isheiban@yahoo.com

Giornale Italiano Di Cardiologia (2006)

|October 24, 2008

Summary

Percutaneous coronary intervention with drug-eluting stents is effective for treating unprotected left main stenosis, a condition previously considered a contraindication. This approach offers favorable early and mid-term outcomes for patients with coronary artery disease.

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Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction

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Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

Published on: April 24, 2017

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction

Published on: August 9, 2022

Area of Science:

Cardiovascular Medicine
Interventional Cardiology

Context:

Significant stenosis of the unprotected left main coronary artery is a prevalent condition linked to adverse cardiovascular events.
Historically, unprotected left main stenosis was a contraindication for percutaneous transluminal coronary angioplasty (PTCA).

Purpose:

To review the clinical management and technical aspects of percutaneous treatment for unprotected left main stenosis.
To provide an updated perspective based on a decade of experience with this specific interventional procedure.

Summary:

The advent of drug-eluting stents has shifted the paradigm, enabling percutaneous revascularization for unprotected left main stenosis.
Multiple studies, including a large meta-analysis, indicate favorable early and mid-term results for PTCA using drug-eluting stents in this patient group.

Impact:

Drug-eluting stents have expanded treatment options for complex coronary artery disease.
This review offers insights for interventional cardiologists managing patients with unprotected left main stenosis.