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A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
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SPROUTS: a database for the evaluation of protein stability upon point mutation

Mathieu Lonquety1, Zoé Lacroix, Nikolaos Papandreou

  • 1Scientific Data Management Laboratory, Arizona State University, Tempe AZ 85282-5706, USA.

Nucleic Acids Research
|October 24, 2008
PubMed
Summary

SPROUTS is a new database offering integrated protein structural analyses, including Most Interacting Residues (MIR) and Tightened End Fragments (TEF). It aids in understanding protein folding and mutation effects.

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