Related Experiment Video

Updated: Jun 28, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

Candida esophagitis: species distribution and risk factors for infection

Dimas Alexandre Kliemann1, Alessandro Comarú Pasqualotto, Maicon Falavigna

  • 1Programa de Pós-Graduação em Ciências Pneumológicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.

Revista Do Instituto De Medicina Tropical De Sao Paulo
|October 25, 2008
PubMed

Insights

Candida esophagitis is primarily caused by Candida albicans, with other species rarely identified. This study found insufficient data to determine risk factors for non-albicans Candida esophagitis.

Area of Science:

  • Medical Mycology
  • Gastroenterology

Background:

  • Candida albicans is the primary cause of fungal esophagitis.
  • Risk factors for non-albicans Candida esophagitis are not well-established.

Purpose of the Study:

  • To determine the etiology of Candida esophagitis.
  • To investigate predisposing conditions for esophageal candidosis caused by different Candida species.

Main Methods:

  • Retrospective analysis of 21,248 upper gastroscopies.
  • Identification of Candida species in esophageal candidosis cases.

Main Results:

  • Prevalence of Candida esophagitis was 0.74% (158 cases).
  • Candida albicans accounted for 96.2% of infections.
  • Other species identified: C. tropicalis (2.5%), C. lusitaniae (0.6%), C. glabrata (0.6%).
  • No mixed infections were observed.
  • 20.8% of patients had no identifiable risk factors.

Conclusions:

  • Candida albicans is the predominant cause of esophagitis.
  • Limited data prevents identifying risk factors for non-albicans Candida esophagitis due to low prevalence.

More Related Videos

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

Related Concept Videos

Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...