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Related Concept Videos

Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
Tetanus01:29

Tetanus

Tetanus is a life-threatening neurological disorder characterized by persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. These bacteria produce terminal endospores, giving them a distinctive “lollipop” or “tennis-racket” appearance. They thrive in anaerobic environments, such as those found in deep puncture wounds.Once introduced into the body, the spores germinate into vegetative cells. These cells...
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Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Three Force Member01:27

Three Force Member

A rigid body subjected to three forces acting at three points is known as a three-force member. These forces must have concurrent lines of action, except for parallel forces, where the lines of action are parallel.
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Assessment of the Cardiovascular System III: Palpation

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Jugular Venous Pressure (JVP) Measurement
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Related Experiment Video

Updated: Jun 28, 2026

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study
08:40

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study

Published on: November 11, 2022

Stiff-three limbs syndrome.

Hélio A G Teive, Renato P Munhoz, Juliana Cardoso

    Movement Disorders : Official Journal of the Movement Disorder Society
    |October 28, 2008
    PubMed
    Summary
    This summary is machine-generated.

    This study details a patient with stiff-three limbs syndrome who showed no continuous motor unit activity. Intravenous immunoglobulin treatment proved effective for this rare neurological condition.

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    Published on: September 16, 2013

    Related Experiment Videos

    Last Updated: Jun 28, 2026

    Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study
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    Published on: September 16, 2013

    Area of Science:

    • Neurology
    • Immunology

    Background:

    • Stiff-three limbs syndrome (STLS) is a rare neurological disorder characterized by progressive muscle stiffness.
    • Electrophysiologic findings in STLS typically include continuous motor unit activity.

    Observation:

    • A patient diagnosed with STLS presented with atypical electrophysiologic findings, notably lacking continuous motor unit activity.
    • This presentation deviated from the established diagnostic criteria for STLS.

    Findings:

    • Despite the atypical electrophysiologic results, the patient responded successfully to treatment.
    • Intravenous immunoglobulin (IVIg) administration led to significant clinical improvement.

    Implications:

    • This case suggests that STLS may present with variable electrophysiologic patterns.
    • Successful IVIg treatment in this atypical case broadens the therapeutic considerations for STLS.
    • Further research is warranted to understand the pathophysiology and diagnostic spectrum of STLS.