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Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR
Published on: February 14, 2016
ASAS centennial paper: Future needs in animal breeding and genetics.
1Pfizer Animal Health, New York, NY 10017, USA. ronnie.green@pfizer.com
Journal of Animal Science
|October 28, 2008
Summary
Animal breeding and genetics are entering the genome era, enabling advanced genetic prediction and precision management. Overcoming challenges like the phenomic gap and training scientists is crucial for future progress.
Area of Science:
- Animal breeding and genetics
- Genomics
- Quantitative genetics
- Systems biology
Background:
- The field has progressed from basic population genetics to sophisticated genetic prediction systems.
- The American Society of Animal Science marks a century of advancement, coinciding with the rise of genome-enabled improvements.
- Recent investments in genomic toolboxes for various livestock species are driving innovation.
Purpose of the Study:
- To highlight the transition of animal breeding and genetics into the genome-enabled era.
- To discuss the potential of genomic toolboxes for whole-genome selection and precision management.
- To identify key challenges and future directions for the field.
Main Methods:
- Development of genomic toolboxes for key livestock species (chicken, bovine, swine, ovine, equine).
- Application of whole-genome selection based on linkage disequilibrium.
- Utilizing systems biology approaches to mine genomes and understand complex interactions.
Main Results:
- Genomic toolboxes facilitate whole-genome selection and redefine genetic prediction based on allele sharing.
- Simultaneous genetic selection and precision management of genotypes are now possible early in an animal's life.
- Systems biology approaches offer insights into gene and metabolic networks, addressing genotype-environment interactions.
Conclusions:
- The field is poised for significant advancements through genome-enabled genetic improvement and precision management.
- Addressing the 'phenomic gap' and a shortage of qualified scientists are critical for realizing genomics' full potential.
- High-quality research and education in animal breeding and genetics remain essential for future progress.
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