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Monoterpenic fragment analogues of aplasmomycin as potential antimalarial
1Department of Chemistry, Indian Institute of Technology, Powai, Bombay.
Journal of Medicinal Chemistry
|September 1, 1991
Abstract:
Seven analogues of monoterpenic fragment of aplasmomycin were synthesized as targeted antimalarial agents. The potency of the compound 6 was comparable with the sesquiterpene lactone artemisinin and the antibiotic aplasmomycin in vivo against Plasmodium berghei yoelli.