Related Experiment Video
Updated: Jun 28, 2026
An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
Published on: January 26, 2024
[Study of the risk factors for ovarian metastasis in patients with endometrial carcinoma]
Long-Yu Li1, Si-Yuan Zeng, Lei Wan
1Department of Gynecologic Oncology, Maternal and Child Health Hospital of Jiangxi Province, Nanchang, China. lilongyu1103@sina.com
Unlabelled:
OBJECTIVE To investigate the risk factors for ovarian metastasis and the possibility of ovarian preservation in patients with endometrial carcinoma.
Methods:
The clinicopathological features of endometrial carcinoma patients who were diagnosed and treated initially with a surgical staging procedure from Jan 1997 to Dec 2006 in our hospital were retrospectively reviewed.
Results:
Of the 638 cases reviewed, 36 (5.6%, 36/638) had ovarian metastasis. Univariate analysis revealed that histological type and grade, myometrial invasion, positive peritoneal fluid cytology, pelvic lymph node metastasis, invasion of parauterine, para-aortic node metastasis and invasion of uterine serosa were significantly associated with ovarian metastasis (P < 0.05); while age, lymph-vascular invasion and cervical invasion were not significantly associated with ovarian metastasis (P > 0.05). Factors predictive of ovarian metastasis by multivariate analysis were ranked as follows according to risk intensity: pelvic lymph node metastasis, positive peritoneal cytology, and histological grade.
Conclusion:
In young patients with grade 1 endometrioid carcinoma, with no pelvic lymph node metastasis, no para-aortic lymph node metastasis, no myometrial invasion and with negative peritoneal fluid cytology, ovarian preservation could be considered.
