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Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
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Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

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Published on: April 22, 2015

Regression in autistic spectrum disorders.

Gerry A Stefanatos1

  • 1Cognitive Neurophysiology Laboratory, Department of Communication Sciences and Disorders, Temple University, 1701 N. 13th St., Philadelphia, PA 19122, USA. Stefang@Temple.edu

Neuropsychology Review
|October 29, 2008
PubMed
Summary
This summary is machine-generated.

Many children with Autistic Spectrum Disorder (ASD) experience developmental regression, losing skills like speech and social responsiveness. This review examines ASD regression characteristics, causes, and its place among other regressive disorders.

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Area of Science:

  • Neurodevelopmental Disorders
  • Pediatric Psychology
  • Developmental Neuroscience

Background:

  • Autistic Spectrum Disorder (ASD) is a neurodevelopmental condition.
  • A subset of children with ASD exhibit developmental regression, a significant loss of previously acquired skills.
  • This regression often involves both speech and social responsiveness.

Purpose of the Study:

  • To critically review the phenomenon of regression in Autistic Spectrum Disorder.
  • To highlight key characteristics including age of onset, temporal course, and long-term outcomes.
  • To discuss diagnostic considerations and review hypothesized etiological factors.

Main Methods:

  • Literature review of studies on regression in Autistic Spectrum Disorder.
  • Critical analysis of existing research on characteristics, diagnosis, and etiology.
  • Conceptualization of regressive ASD within a broader spectrum of regressive disorders.

Main Results:

  • Developmental regression in ASD is characterized by a loss of speech and/or social responsiveness.
  • The age of onset, temporal course, and long-term outcomes vary.
  • Multiple etiological factors are hypothesized, but not definitively established.

Conclusions:

  • Regressive Autistic Spectrum Disorder can be viewed as part of a spectrum with other regressive disorders.
  • Shared pathophysiological features may exist between regressive ASD and other regressive conditions.
  • This conceptualization has implications for understanding, diagnosis, and potential treatments.