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Related Concept Videos

Gas Chromatography–Mass Spectrometry (GC–MS)01:14

Gas Chromatography–Mass Spectrometry (GC–MS)

Gas chromatography–mass spectrometry (GC–MS) is the combination of analytical techniques of gas chromatography and mass spectrometry in a single instrument for analyzing a mixture of compounds. The gas chromatograph separates the compounds in the mixture, and the mass spectrometer analyzes each compound separately to determine the molecular masses and molecular structures.
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall. The coating...
Gas Chromatography: Introduction01:13

Gas Chromatography: Introduction

Gas chromatography (GC) is a technique for separating and analyzing volatile compounds in a sample. Its primary purpose is to identify and quantify components in complex mixtures, making it essential in fields such as environmental analysis, pharmaceuticals, and petrochemicals. GC is also called vapor-phase chromatography (VPC) or gas-liquid partition chromatography (GLPC).
In GC,  a sample is vaporized and mixed with an inert carrier gas (the mobile phase), which transports it through a column.
Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
Supercritical Fluid Chromatography01:18

Supercritical Fluid Chromatography

Supercritical fluid chromatography (SFC) provides a beneficial substitute for gas chromatography (GC) and liquid chromatography (LC) for certain samples because it merges the top attributes of both techniques. SFC allows the separation and analysis of compounds that GC or LC does not easily manage. These compounds are traditionally nonvolatile or thermally unstable, making GC unsuitable and lacking functional groups required for HPLC analysis.
SFC utilizes a supercritical fluid mobile phase,...
Gas Chromatography: Overview of Detectors01:13

Gas Chromatography: Overview of Detectors

Detectors in gas chromatography (GC) help identify and quantify the components of a mixture by translating chemical properties into measurable signals, which are displayed on a chromatogram. Detectors can be categorized into two main types: destructive and non-destructive.
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...

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Updated: Jun 28, 2026

Measurement of H2S in Crude Oil and Crude Oil Headspace Using Multidimensional Gas Chromatography, Deans Switching and Sulfur-selective Detection
08:37

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Organosulphur behaviour in a GC/MS membrane interface.

M Thompson1, M Stanisavljević

  • 1Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 1A1, Canada.

Talanta
|October 1, 1982
PubMed
Summary
This summary is machine-generated.

This study investigated sulfur compounds like dimethyldisulfide and thiols in a specialized gas chromatography interface. The all-Teflon system showed consistent behavior for trace sulfur analysis.

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Area of Science:

  • Analytical Chemistry
  • Environmental Science

Background:

  • Trace sulfur compounds are critical in environmental monitoring and industrial processes.
  • Accurate detection of volatile sulfur compounds requires robust analytical interfaces.
  • Previous studies have explored various materials for gas chromatography interfaces, but sulfur compound behavior requires specific investigation.

Purpose of the Study:

  • To evaluate the behavior of low-concentration sulfur compounds (0.1-1.0 ng) within a membrane gas-chromatograph/mass-spectrometer interface.
  • To assess the performance of an all-Teflon system with different membrane housing materials (glass vs. polymer).
  • To determine the suitability of the interface for precise quantification of volatile sulfur analytes.

Main Methods:

  • Utilized a membrane gas-chromatograph/mass-spectrometer interface constructed with an all-Teflon system.
  • Investigated the behavior of dimethyldisulfide, n-butanethiol, and diisopropylsulphide.
  • Employed membrane housings made of either glass or polymer for comparative analysis.
  • Analyzed trace amounts of sulfur compounds ranging from 0.1 to 1.0 ng.

Main Results:

  • The all-Teflon system demonstrated predictable behavior for the studied sulfur compounds.
  • Results indicated no significant difference in compound behavior based on glass versus polymer membrane housing.
  • The interface effectively handled and analyzed trace levels of volatile sulfur compounds.

Conclusions:

  • The all-Teflon membrane gas-chromatograph/mass-spectrometer interface is suitable for the analysis of low-level sulfur compounds.
  • Material choice for the membrane housing (glass or polymer) did not adversely affect the analysis of these specific sulfur compounds.
  • The system provides a reliable method for trace sulfur analysis in relevant applications.