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Updated: Jun 28, 2026

Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method
Published on: December 25, 2016
A new method for the voltammetric determination of nitrite
1Institut für Analytische Chemie, Karl-Franzens Universität, Universitätsplatz 1, A-8010 Graz, Austria.
A new voltammetric method uses a modified carbon-paste electrode to detect nitrite. This technique allows for the sensitive determination of trace nitrite concentrations, reaching as low as 1 ng/ml.
Area of Science:
- Electrochemistry
- Analytical Chemistry
Background:
- Nitrite is an important analyte in various environmental and biological samples.
- Accurate determination of trace nitrite levels is crucial for monitoring and safety.
Purpose of the Study:
- To develop a sensitive and reliable voltammetric method for nitrite determination.
- To utilize a chemically modified electrode for enhanced nitrite detection.
Main Methods:
- Development of a carbon-paste electrode chemically modified with an anion-exchanger.
- Application of voltammetric techniques for nitrite analysis.
- Exploitation of nitrite accumulation on the electrode surface.
Main Results:
- The modified electrode enables sensitive detection of nitrite.
- Trace nitrite concentrations as low as 1 ng/ml can be accurately determined.
- The method offers a viable approach for quantifying low nitrite levels.
Conclusions:
- The developed voltammetric method with a modified carbon-paste electrode is effective for trace nitrite determination.
- The anion-exchanger modification enhances nitrite accumulation and detection sensitivity.
- This method provides a valuable tool for sensitive nitrite analysis.
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