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Determination of levamisole hydrochloride with HgI(2-)4 by a turbidimetric method and flow-injection analysis
1Departamento de Química Analítica, Facultad de Química, Universidad de Valencia, Burjasot Valencia, Spain.
Abstract:
This paper is concerned with the use of ion-association compounds in the analysis of pharmaceutical samples by FIA. The usual extraction into an organic phase is avoided by using turbidimetric detection. Determination of levamisole with HgI(2-)(4) has been developed as a practical example: the experimental variables were optimized by the modified simplex method. The calibration graph is linear over the levamisole concentration range 7-32 microg ml . The reproducibility (rsd) and injection sample rate are 0.9% and 80/hr, respectively.
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