Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Assessment of Diffusion and Perfusion

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

Pulse Oximetry

Pulse Oximetry

Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...

Coulometry: Overview

Coulometry: Overview

Coulometry is one of the rapid, most accurate, and precise analytical techniques that determine the quantity of an analyte by measuring the electrical charge needed for its complete electrolysis without using any analytical standards. The total charge passed during electrolysis correlates with the analyte amount by Faraday's laws of electrolysis. For accurate coulometric measurements, a charge equal to Faraday's constant multiplied by the number of electrons involved in the relevant...

Special considerations while measuring oxygen saturation

Special considerations while measuring oxygen saturation

Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.

Fluorescence and Phosphorescence: Instrumentation

Fluorescence and Phosphorescence: Instrumentation

Fluorometers and spectrofluorometers are two types of instruments used for measuring molecular fluorescence. These instruments differ in how they select excitation and emission wavelengths and the type of light sources they utilize. Fluorometers use absorption interference filters to choose excitation and emission wavelengths. The excitation source in a fluorometer is typically a low-pressure mercury vapor lamp that emits intense lines distributed throughout the ultraviolet and visible regions.

Electronic Distance Measuring Instruments

Electronic Distance Measuring Instruments

Electronic Distance Measuring Instruments (EDMs) are essential tools in modern surveying, offering precise distance measurements by emitting electromagnetic signals and calculating the time required for these signals to travel to a target and return. Two primary types of signals are used in EDMs — light waves and microwaves — each suited to specific environmental and distance requirements. Light-wave-based EDMs utilize either infrared or laser light, providing high accuracy over short distances...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Enzyme Kinetics in Femtoliter Arrays.

Methods in enzymology·2016

Same author

pH-Dependent fluorescence and singlet energy transfer in water-soluble polymers containing eosin and phenol red chromophores.

Journal of fluorescence·2013

Same author

Whole-saliva proteolysis and its impact on salivary diagnostics.

Journal of dental research·2011

Same author

An Autonomous Sensor and Telemetry System for Low-Level pCO(2) Measurements in Seawater.

Analytical chemistry·2011

Same author

An Autonomous Sensor and Telemetry System for Low-Level pCO(2) Measurements in Seawater.

Analytical chemistry·2011

Same author

Generating Sensor Diversity through Combinatorial Polymer Synthesis.

Analytical chemistry·2011

Same journal

Detection and cross-organ characterization of physiological response to microplastic stress in Panax ginseng based on hyperspectral imaging assisted with machine learning.

Talanta·2026

Same journal

Electron-driven proton transfer behaviors in oxidative DNA lesion 8-oxoguanine: A computational study.

Talanta·2026

Same journal

TiO<sub>2</sub> nanoengineering for high-performance photoelectrochemical biosensors: From fundamental strategies to frontier applications.

Talanta·2026

Same journal

CRISPR-based diagnostics for ESKAPE drug-resistant bacteria: From proof-of-concept to point-of-care.

Talanta·2026

Same journal

Integrated 3D printed wearable microfluidics with removable electrochemical sensor for morphine monitoring in sweat.

Talanta·2026

Same journal

Eu-doped Tourmaline@MOF-ZnO core-shell nanocomposites: Enabling UV-activated room-temperature and ppb-level n-butanol sensing.

Talanta·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 28, 2026

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

Published on: January 7, 2019

A fiber-optic sensor for CO(2) measurement.

C Munkholm¹, D R Walt, F P Milanovich

¹Max Tishler Laboratory for Organic Chemistry, Department of Chemistry, Tufts University, Medford, MA 02155, U.S.A.

|February 1, 1988

Summary

This summary is machine-generated.

A new fiber-optic sensor detects carbon dioxide (CO2) at physiologically relevant levels. This miniature sensor uses a fluorescent dye and pH changes for accurate CO2 measurement in biological applications.

More Related Videos

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Published on: November 7, 2016

Related Experiment Videos

Last Updated: Jun 28, 2026

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

Published on: January 7, 2019

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Published on: November 7, 2016

Area of Science:

Biomedical Engineering
Chemical Sensors
Optical Sensing

Background:

Accurate monitoring of carbon dioxide (CO2) is crucial in physiological and medical settings.
Existing CO2 sensors can be bulky or lack the sensitivity required for certain applications.
Developing miniature, sensitive sensors is essential for advanced biomedical monitoring.

Purpose of the Study:

To develop a novel fiber-optic sensor for detecting carbon dioxide.
To achieve sensitivity at physiologically significant CO2 concentrations.
To preserve the miniature size of the sensor through advanced fabrication techniques.

Main Methods:

Fabrication of a fiber-optic sensor utilizing a fluorescent dye-based sensing layer.
Immobilization of sensing chemistry directly onto the glass fiber tip using solution polymers.
Preparation of polymer-immobilized dyes and polymer membranes for sensor construction.

Main Results:

The developed fiber-optic sensor exhibits a response to carbon dioxide.
The sensor operates effectively at physiologically significant CO2 concentrations.
The direct bonding methodology preserves the sensor's miniature dimensions.

Conclusions:

A functional fiber-optic sensor for CO2 detection has been successfully prepared.
The sensor's design is suitable for applications requiring precise CO2 monitoring.
The polymer immobilization technique offers a robust method for creating miniature optical sensors.