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Nifedipine: Differential pulse polarography and photodecomposition
J A Squella1, E Barnafi, S Perna
1Laboratorio de Electroquimica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, P.O.B. 233 Santiago, Chile.
Abstract:
A method for the differential-pulse polarographic determination of nifedipine has been developed, based on the electrochemistry of the aromatic nitro group in the drug. Polarography has also been used in studies of the photodegradation of nifedipine, which is highly light-sensitive under ultraviolet light and artificial daylight.
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