Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...
Ion-Exchange Chromatography01:09

Ion-Exchange Chromatography

Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
Capillary Electrophoresis: Applications01:30

Capillary Electrophoresis: Applications

Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Probing electrical double layer via triboelectric charge transfer.

Nature communications·2025
Same author

Use of Prussian Blue pseudocapacitive properties to amplify the pulsed amperometric readout of biosensors.

Biosensors & bioelectronics·2025
Same author

Functional hydrogels-enabling the gateway for sustainable water treatment and harvesting technologies.

Environmental research·2025
Same author

Carbon Black and PEDOT:PSS in a Synergistic Solid Contact for Reliable Printed Potentiometric Sensors.

ACS sensors·2025
Same author

Influence of electrode body material on the analytical behaviour of solid-contact ion-selective electrodes.

Talanta·2025
Same author

EACH Erasmus Mundus programme: advancing excellence in analytical chemistry education and industry impact.

Analytical and bioanalytical chemistry·2025

Related Experiment Video

Updated: Jun 28, 2026

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
08:03

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Small-volume radial flow cell for all-solid-state ion-selective electrodes.

Mercedes Vázquez1, Johan Bobacka, Ari Ivaska

  • 1Process Chemistry Group, c/o Centre for Process Analytical Chemistry and Sensor Technology (ProSens), Abo Akademi University, FIN-20500, Abo-Turku, Finland.

Talanta
|October 31, 2008
PubMed
Summary
This summary is machine-generated.

A novel flow cell design for mass-produced, all-solid-state ion-selective electrodes (ISEs) minimizes contamination and volume. This optimized design is suitable for clinical analysis applications.

More Related Videos

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique
09:18

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique

Published on: May 3, 2015

A Protocol for Electrochemical Evaluations and State of Charge Diagnostics of a Symmetric Organic Redox Flow Battery
09:49

A Protocol for Electrochemical Evaluations and State of Charge Diagnostics of a Symmetric Organic Redox Flow Battery

Published on: February 13, 2017

Related Experiment Videos

Last Updated: Jun 28, 2026

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
08:03

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique
09:18

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique

Published on: May 3, 2015

A Protocol for Electrochemical Evaluations and State of Charge Diagnostics of a Symmetric Organic Redox Flow Battery
09:49

A Protocol for Electrochemical Evaluations and State of Charge Diagnostics of a Symmetric Organic Redox Flow Battery

Published on: February 13, 2017

Area of Science:

  • Electrochemistry
  • Analytical Chemistry
  • Materials Science

Background:

  • All-solid-state ion-selective electrodes (ISEs) are crucial for chemical analysis.
  • Minimizing cell volume and cross-contamination is essential for improved performance.
  • Developing cost-effective manufacturing methods for ISEs is a key challenge.

Purpose of the Study:

  • To design and optimize a novel flow cell for mass production of all-solid-state ISEs.
  • To evaluate different methods for incorporating a conducting polymer as a solid internal contact.
  • To assess the suitability of the developed flow cell for clinical analysis.

Main Methods:

  • A flow cell with radially distributed electrodes was designed and optimized.
  • Two prototypes of all-solid-state potassium ion-selective electrodes (K(+)-ISEs) were developed.
  • Poly(3,4-ethylenedioxythiophene) (PEDOT) was used as a solid internal contact, with two deposition methods tested: electropolymerization and solution casting of a PEDOT dispersion.

Main Results:

  • The radial electrode distribution effectively reduced cell volume (17-37 µL) and minimized cross-contamination.
  • Solution casting of a commercially available PEDOT(PSS) dispersion proved advantageous for mass production compared to electropolymerization.
  • The developed flow cell prototypes demonstrated suitability for K(+)-ISE applications.

Conclusions:

  • The optimized radial flow cell design offers a scalable solution for manufacturing all-solid-state ISEs.
  • Solution casting of PEDOT dispersions is a viable and advantageous method for industrial production of ISEs.
  • The small-volume, low-contamination flow cell is well-suited for clinical analysis and other high-throughput applications.