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Updated: Jun 28, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Published on: July 4, 2018

[Supportive care. Treating pain].

¹Arnold Pain Management Center, Beth Israel Deaconess Medical Center, Harvard Medical School, One Brookline Place, Brookline, MA 02445, USA. cpeeters@bidmc.harvard.edu

Revue Des Maladies Respiratoires

|November 26, 2008

Summary

This summary is machine-generated.

Cancer pain management remains a challenge, with many patients experiencing undertreated pain. This overview covers various therapeutic options, from the World Health Organization (WHO) ladder to advanced interventions and complementary therapies.

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Last Updated: Jun 28, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Published on: July 4, 2018

Area of Science:

Neuroscience
Pharmacology
Oncology

Context:

Despite advances in pain neuroscience and pharmacologic treatments, significant numbers of cancer patients suffer from inadequately managed pain.
Effective cancer pain control is crucial for patient quality of life and treatment adherence.

Purpose:

To provide a comprehensive overview of current and emerging therapeutic modalities for managing cancer pain.
To discuss the World Health Organization (WHO) analgesic ladder, invasive procedures, and alternative therapies.

Summary:

This article reviews diverse cancer pain management strategies, including the WHO analgesic ladder, intrathecal drug delivery, neurostimulation, radiofrequency ablation, acupuncture, and palliative care.
It highlights the need for multimodal approaches to address the complexities of cancer-related pain.

Impact:

This review aims to guide clinicians in selecting appropriate pain management strategies for cancer patients.
Improved understanding and application of these therapies can lead to better pain relief and enhanced patient outcomes in oncology.