Related Experiment Video
Updated: Sep 23, 2026

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer
Published on: April 21, 2022
[Respiratory mucus: Exploring its viscoelastic properties and their relationship with mucociliary clearance
T Bonneault1, C Sallon1, C Taillé2
1Équipe InnaLung, unité U1149, Inserm, université Paris Cité, 75018 Paris, France.
Abstract:
Following an introduction on the structure and function of the respiratory mucus, we describe the viscoelastic properties of mucus, a key determinant of mucociliary clearance, along with the types of measurement devices most commonly used in laboratories. More specifically, this review presents macro- and micro-rheological methods for characterization of the respiratory mucus by means of small sample volumes. We discuss how study of the viscoelastic properties of mucus facilitates understanding of mucus abnormalities in respiratory muco-obstructive diseases and paves the way for the development of therapies effectively targeting mucin cross-linking molecules in view of enhancing patient management.
Related Concept Videos
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Respiratory System Abnormal Finding II: Palpation and Auscultation
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Pressure Relationships in Thoracic Cavity
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs during...
