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Updated: Jun 28, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
[Study on optimization of the hydrolysis process of dioscin catalyzed by hydrochloric acid]
Qian Li1, Xiang-Tao Gao, Wen-Lei Zhao
1Institute of Fine Chemistry and Engineering, Kaifeng 475001, China. liq@henu.edu.cn
Objective:
To study the optimization of hydrolysis process of dioscin catalyzed by hydrochloric acid.
Methods:
The effects of hydrochloric acid concentration, reaction temperature, reaction time and their interactions had been investigated using orthogonal design and single-factor experiments.
Results:
The optimum hydrolysis conditions were as follows: reaction temperature 90 degrees C, reaction time 3h, hydrochloric acid concentration 2.0 mol/L.
Conclusion:
Hydrochloric acid concentration and reaction temperature should be controlled because of their remarkable influence on hydrolysis process.
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