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Updated: Jun 28, 2026

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
Published on: October 2, 2018
Gap junctions as modulators of adrenal cortical cell proliferation and steroidogenesis
S A Murray1, B M Nickel, V L Gay
1Department of Cell Biology and Physiology, University of Pittsburgh, School of Medicine, Pittsburgh, PA l5261, United States. smurray@pitt.edu
Abstract:
Gap junctions are membrane specializations that are composed of connexin protein. The assembly of these proteins into channels between cells allows for the intercellular transfer of regulatory molecules. In the adrenal gland, as in most other tissues, intercellular communication provides the potential for regulation of a number of complex interactive cell processes including differentiation, steroidogenesis, migration, and proliferation. This review is concerned with the regulation of gap junctions and cell function in cortical cells of the adrenal gland and in pathological disorders such as adrenal cancer.
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