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3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

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Published on: October 24, 2019

Streaking artifacts reduction in four-dimensional cone-beam computed tomography.

Shuai Leng¹, Joseph Zambelli, Ranjini Tolakanahalli

¹Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53792, USA.

Medical Physics

|November 4, 2008

Summary

This summary is machine-generated.

This study introduces a novel method to reduce streaking artifacts in four-dimensional cone-beam CT (4D CBCT) used in radiation therapy. The technique significantly improves image quality by leveraging a prior image reconstruction for motion artifact reduction.

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Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

Area of Science:

Medical Imaging
Radiation Oncology
Image Reconstruction

Background:

Gantry-mounted Cone-beam CT (CBCT) in image-guided radiation therapy (IGRT) faces challenges with patient motion during slow projection acquisition.
Four-dimensional CBCT (4D CBCT) aims to reduce motion artifacts by sorting data by respiratory phase, but severe undersampling artifacts persist due to limited projections.

Purpose of the Study:

To develop and validate a method for significantly reducing streaking artifacts in 4D CBCT images.
To improve the quality of 4D CBCT for enhanced patient positioning and adaptive treatment planning in radiation therapy.

Main Methods:

A prior image is reconstructed from all projections without gating to capture static structures.
Undersampling artifacts from static structures are estimated from the prior image.
Artifacts are removed from gated phase images using the estimated artifact information.

Main Results:

The proposed method effectively reduces streaking artifacts by 60% to 70% compared to conventional 4D CBCT.
Image fidelity of both stationary and moving objects is maintained.
Reconstruction is achievable within a standard 60-second scan time with a narrow 100 ms temporal gating window.

Conclusions:

The developed scheme offers a simple yet effective solution for mitigating undersampling artifacts in 4D CBCT.
This technique enhances the clinical utility of 4D CBCT for image-guided radiation therapy by improving image quality and artifact reduction.