[Changes in the liver circulation and kidney function during pulsatile and non-pulsatile perfusion]

Pulsatile flow perfusion (PFP) requires smaller volume of additional infusion. Extravascular hyperhydration is more marked after nonpulsatile flow perfusion (NPFP). In NPFP there is an increase in free water clearance, lower urinary osmolality and diuresis rate. PFP prevents urinary hypoosmolality and retains baseline values of free water clearance. No significant differences in Na+ urinary excretion have been revealed. Bilirubinemia level following NPFP was significantly higher than the baseline level, while following PFP the level of total and bound bilirubin remained unchanged. No differences in the total hepatic flow have been observed during pulsatile and nonpulsatile flow perfusion.