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Clinical implications of unmanaged needle-insertion pain and distress in children
Robert M Kennedy1, Janet Luhmann, William T Zempsky
1Department of Pediatrics, Division of Emergency Medicine, Washington University in St Louis School of Medicine, St Louis, Missouri, USA. kennedy@kids.wustl.edu
Insights
Pediatric procedural pain, like from venipuncture, significantly impacts children. Effective pharmacologic and nonpharmacologic methods can reduce this acute pain and distress.
Area of Science:
- Pediatric Pain Management
- Neuroscience of Pain
Background:
- Venipuncture and cannulation are significant sources of pediatric pain with lasting effects.
- Infants' pain pathways mature postnatally, potentially increasing pain intensity compared to older children.
- Early painful experiences can heighten later pain responses, even with improved analgesia.
Purpose of the Study:
- To review the evidence on the importance of managing pediatric procedural pain.
- To summarize methods for reducing pain associated with venous access procedures in children.
Main Methods:
- Literature review of studies on pediatric procedural pain.
- Synthesis of evidence on pharmacologic and nonpharmacologic pain management techniques.
Main Results:
- Pain from venipuncture and IV cannulation is a critical pediatric pain issue.
- Both pharmacologic and nonpharmacologic interventions effectively reduce acute pain and distress.
- Early pain management is crucial for preventing long-term negative behavioral responses.
Conclusions:
- Effective management of pediatric procedural pain, especially venous access pain, is essential.
- A combination of pharmacologic and nonpharmacologic strategies can mitigate pain and distress.
- Addressing initial pain experiences can prevent sensitization and reduce future pain burdens.
Abstract:
Increasing evidence has demonstrated that pain from venipuncture and intravenous cannulation is an important source of pediatric pain and has a lasting impact. Ascending sensory neural pain pathways are functioning in preterm and term infants, yet descending inhibitory pathways seem to mature postnatally. Consequently, infants may experience pain from the same stimulus more intensely than older children. In addition, painful perinatal procedures such as heel lancing or circumcision have been found to correlate with stronger negative responses to venipuncture and intramuscular vaccinations weeks to months later. Similarly, older children have reported greater pain during follow-up cancer-related procedures if the pain of the initial procedure was poorly controlled, despite improved analgesia during the subsequent procedures. Fortunately, both pharmacologic and nonpharmacologic techniques have been found to reduce children's acute pain and distress and subsequent negative behaviors during venipuncture and intravenous catheter insertion. This review summarizes the evidence for the importance of managing pediatric procedural pain and methods for reducing venous access pain.
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