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Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

Published on: October 2, 2020

A visual analytics system for breast tumor evaluation.

Sokol Petushi¹, Jeffrey Marker, Jasper Zhang

¹Department of Pathology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA. spetushi@drexelmed.edu

Analytical and Quantitative Cytology and Histology

|November 5, 2008

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This study developed an interactive visual analytics system for breast tumor evaluation. The system integrates histologic data, 2D/3D imaging, and prognostic information for enhanced analysis.

Area of Science:

Digital pathology
Medical imaging
Computational biology

Background:

Histologic grading of breast tumors is crucial for prognosis.
Current methods may benefit from advanced computational tools for data integration and visualization.

Purpose of the Study:

To develop an interactive system for exploring and examining histologic data of breast tumors.
To aid in the evaluation of tumor histologic grade using integrated data.

Main Methods:

Integration of pathologist-generated prognostic data with 2D/3D image analysis.
Development of a system with a user interface for image processing, 3D reconstruction, and volumetric analysis.
Implementation of a web-based database for interactive data browsing, searching, and multimodality visualization.

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Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound

Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound

Published on: August 14, 2012

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Last Updated: Jun 28, 2026

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

Published on: October 2, 2020

Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound

Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound

Published on: August 14, 2012

Main Results:

The developed system has been successfully implemented and deployed.
Data from 36 breast cancer cases were utilized, with 7 tumors reconstructed in 3D.

Conclusions:

Interactive visual analytics technology offers an effective approach for breast tumor evaluation.
The system facilitates comprehensive analysis of histologic and prognostic data for improved understanding of breast tumors.