Related Experiment Videos
[Transient myocardial ischemia and isolated congenital mitral valve prolapse in an infant]
J P Guthmann1, A M Rossignol, J E Wolf
1Département de médecine et réanimation pédiatrique, CHU de Grenoble.
Insights
Congenital mitral regurgitation in an infant was linked to myocardial ischemia. This rare complication, usually seen in adults with mitral valve prolapse, highlights potential infant cardiac risks.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Cardiovascular Pathology
Background:
- Congenital mitral regurgitation (CMR) can arise from various cardiac anomalies.
- Mitral valve prolapse (MVP) is a known cause of valvular dysfunction.
- Myocardial ischemia in infants is often associated with specific congenital conditions.
Observation:
- A 9-month-old infant presented with a cardiac murmur.
- Clinical, echocardiographic, and angiographic evaluations confirmed isolated mitral valve prolapse causing congenital mitral regurgitation.
- Electrocardiogram revealed signs of inferior myocardial ischemia.
Findings:
- The infant's myocardial ischemia resolved spontaneously within one week.
- This case suggests a potential link between mitral valve prolapse and myocardial ischemia in infancy.
- Coronary spasm-induced ischemia is a recognized complication of MVP in adults.
Implications:
- This report may be the first to describe myocardial ischemia as a complication of mitral valve prolapse in infancy.
- It underscores the importance of considering rare cardiac complications in pediatric patients with valvular abnormalities.
- Further research is warranted to understand the pathophysiology and incidence of MVP-related ischemia in infants.
Abstract:
The investigation of a cardiac murmur in a 9 month old infant led to the clinical, echo and angiographic diagnosis of congenital mitral regurgitation due to isolated mitral valve prolapse, whereas the electrocardiogram showed signs of inferior myocardial ischaemia which regressed in a week. The valvular dysfunction of mitral valve prolapse has been held responsible for coronary spasm ischaemia and infarction in adults. This complication has not been previously reported to our knowledge in infancy.