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Atrial fibrillation after cardiac surgery: where are we now?
Dimpi Patel1, Marc A Gillinov, Andrea Natale
1St. David's Medical Center,Austin, TX 78744, USA. dimpi.patel@stdavids.com
Insights
Postoperative atrial fibrillation (POAF) affects 25-60% of cardiac surgery patients, increasing risks. Prophylaxis is recommended, with specific strategies for symptomatic or unstable patients versus others.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery.
- It significantly increases patient morbidity, mortality, and hospital length of stay.
Purpose of the Study:
- To comprehensively review the pathophysiology, risk factors, prophylaxis, and treatment of POAF.
- To outline future research directions in POAF management.
Main Methods:
- A systematic literature search was conducted using Medline database from January 1966 to September 2008.
- Keywords included "Atrial fibrillation," "Postoperative atrial fibrillation," "Coronary Artery Bypass," and "antiarrhythmic agents."
- References from relevant articles were also reviewed.
Main Results:
- POAF incidence ranges from 25% to 60%, varying with the type of cardiac surgery.
- POAF typically manifests on postoperative days 2 or 3.
- POAF is linked to elevated risks of complications and prolonged hospitalization.
Conclusions:
- Prophylactic interventions can decrease the incidence of POAF.
- Symptomatic and hemodynamically unstable patients with POAF should receive rhythm control strategies.
- Asymptomatic or stable patients with POAF are best managed with rate control strategies.
Objective:
To review: 1) Pathophysiology of postoperative atrial fibrillation (POAF); 2) Risk factors for POAF; 3) Prophylaxis of POAF; 4) Treatment of POAF; and 5) Future directions.
Methods:
We searched the Medline database for articles published between January, 1966 to September, 2008. We used the following keywords: Atrial fibrillation, Postoperative atrial fibrillation, Coronary Artery Bypass, and antiarrhythmic agents. Additionally, we searched references from all relevant articles.
Conclusions:
POAF occurs in 25-60% of patients depending on the type of cardiac surgery performed. POAF generally occurs on postoperative day 2 or 3. POAF is associated with an increased risk of morbidity and mortality, and longer hospital stay. Prophylactic treatments reduce the likelihood of POAF. In patients who experience POAF, rhythm strategies should be used in those who are symptomatic and hemodynamically unstable. All other patients should be managed with rate strategies.
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