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Atypical mycobacterial cutaneous infections
Sanjay Bhambri1, Avani Bhambri, James Q Del Rosso
1Valley Hospital Medical Center, Medical Education Department, 620 Shadow Lane, Las Vegas, NV 89106, USA. sbhambri18@hotmail.com
Dermatologic Clinics
|November 6, 2008
Summary
Atypical mycobacterial infections are increasing, particularly in immunocompromised individuals. Treatment typically involves multiple drugs and surgery due to a lack of specific guidelines.
Area of Science:
- Microbiology
- Infectious Diseases
- Immunology
Background:
- Atypical mycobacterial infections show a growing prevalence, especially in immunocompromised patients.
- These ubiquitous environmental bacteria are classified by pigment production, growth rate, and optimal temperature.
- Examples include slow-growing Mycobacterium marinum and rapidly growing Mycobacterium fortuitum.
Purpose of the Study:
- To review the classification and treatment of atypical mycobacterial infections.
- To highlight the challenges in managing these infections due to lack of specific guidelines.
Main Methods:
- Classification based on phenotypic characteristics (pigment, growth rate, temperature).
- Review of current therapeutic approaches, including multidrug regimens and surgical interventions.
Main Results:
- Atypical mycobacteria are categorized into slow-growing and rapidly growing groups.
- No definitive treatment guidelines exist for these infections.
- Combined multidrug and surgical therapy is a common management strategy.
Conclusions:
- Atypical mycobacterial infections represent a significant and increasing public health concern.
- Effective management requires a comprehensive approach due to the absence of standardized treatment protocols.
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