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Updated: Jun 28, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
[Myocardial perfusion scintigraphy. Exact and cost-effective coronary disease imaging--secondary publication]
Birger Hesse1, Claus Leth Petersen, Claudio Marcassa
1Rigshospitalet, Klinik for Klinisk Fysiologi og Nuklearmedicin og PET, og Frederiksberg Hospital, Afdeling for Klinisk Fysiologi og Nuklearmedicin. bhesse@rh.regionh.dk
Insights
Coronary arterial disease (CAD) mortality is decreasing, yet it remains a leading cause of death. Myocardial perfusion scintigraphy (MPS) is a valuable, cost-effective tool for early CAD detection and risk stratification in symptomatic patients.
Area of Science:
- Cardiology
- Nuclear Medicine
- Diagnostic Imaging
Background:
- Coronary arterial disease (CAD) remains the primary cause of mortality globally.
- Despite declining rates, CAD necessitates effective early detection and risk assessment strategies.
Purpose of the Study:
- To highlight the role of myocardial perfusion scintigraphy (MPS) in managing coronary arterial disease.
- To emphasize MPS as a cost-effective diagnostic tool for symptomatic individuals.
Main Methods:
- Review of existing evidence supporting the clinical applications of MPS.
- Analysis of MPS's utility in patient risk stratification and clinical decision-making.
Main Results:
- MPS is a cost-effective method for the early detection of CAD.
- MPS effectively stratifies patients based on their risk of cardiac events.
- MPS provides crucial data that aids in clinical decision-making.
Conclusions:
- Myocardial perfusion scintigraphy (MPS) is an integral component of current clinical practice guidelines for CAD.
- The evidence base strongly supports the established applications of MPS in cardiology.
Abstract:
Mortality rates due to coronary arterial disease (CAD) have declined as result of improved prevention, diagnosis and management, but CAD remains the leading cause of death. Myocardial perfusion scintigraphy (MPS) provides a cost-effective tool for early detection of CAD in symptomatic individuals and can stratify patients according to risk of cardiac events. MPS also provides valuable information to assist clinical decision-making. A large body of evidence supports the current applications of MPS, which has become integral to several guidelines for clinical practice.
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