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Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
Ischaemic stroke with ovarian hyperstimulation syndrome
Amna Qazi1, Aamir Nazir Ahmed, Mah Parveen Qazi
1Department of Medicine, Shifa International Hospital and College of Medicine, H-8/4, Islamabad, Pakistan.
JPMA. the Journal of the Pakistan Medical Association
|November 8, 2008
Summary
Ovarian hyperstimulation syndrome (OHSS) can cause serious blood clots. This case highlights a rare stroke complication in a patient undergoing fertility treatment, emphasizing the need for vigilance.
Area of Science:
- Reproductive Endocrinology
- Neurology
- Vascular Medicine
Background:
- Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ovulation induction therapies.
- It involves fluid shifts leading to hemoconcentration and increased thrombosis risk.
- Reported thromboembolic events include stroke and venous thrombosis.
Observation:
- A 30-year-old female presented with sudden left hemiplegia post-in vitro fertilization.
- CT scan revealed a right middle cerebral artery (MCA) territory infarct.
- MRI confirmed hemorrhagic conversion of the infarct.
Findings:
- The patient experienced an ischemic stroke attributed to OHSS-related hyperviscosity.
- Treatment included aspirin, plasma expanders, and mannitol.
- The stroke converted to a hemorrhagic infarct.
Implications:
- This case underscores the potential for severe neurological complications in OHSS.
- Highlights the importance of recognizing thromboembolic risks associated with fertility treatments.
- Suggests the need for careful monitoring and management of OHSS patients for neurological events.
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