Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Insufficient use of anticoagulants in geriatric in-patients with atrial fibrillation and flutter].

Deutsche medizinische Wochenschrift (1946)·2015
Same author

[Insufficient use of anticoagulants in geriatric in-patients with atrial fibrillation and flutter (corrected)].

Deutsche medizinische Wochenschrift (1946)·2015
Same author

Obturator nerve injury in laparoscopic inguinal hernia mesh repair.

Hernia : the journal of hernias and abdominal wall surgery·2012
Same author

Study of Mn interstitials in (Ga, Mn)As using high-resolution x-ray diffraction.

Journal of physics. Condensed matter : an Institute of Physics journal·2011
Same author

Effect of Flavobacterium columnare inoculation, antibiotic treatments and resident bacteria on rainbow trout Oncorhynchus mykiss eyed egg survival and external membrane structure.

Journal of fish biology·2010
Same author

[Can the sacral spongiosa bleeding cause fatal complications of unstable pelvic fracture?].

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2010
Same journal

Rare causes of pneumoperitoneum.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2026
Same journal

Imaging of pneumoperitoneum.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2026
Same journal

Postoperative pneumoperitoneum.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2026
Same journal

Pneumoperitoneum of the lower gastrointestinal tract.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2026
Same journal

Pneumoperitoneum in dis-eases and traumas of the upper part of the digestive tract -  an overview of current knowledge and clinical context.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2026
Same journal

Pseudoaneurysm arteria carotis.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2026
See all related articles

Related Experiment Video

Updated: Jun 28, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

[Clostridium difficile colitis].

D Bergmann1, L Horák

  • 1II. interní klinika FTNsP v Praze.

Rozhledy V Chirurgii : Mesicnik Ceskoslovenske Chirurgicke Spolecnosti
|November 8, 2008
PubMed
Summary
This summary is machine-generated.

Clostridium difficile infections are increasingly common, especially in surgical patients. This study details the pathogenesis, diagnosis, and treatment of these challenging conditions.

More Related Videos

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

Related Experiment Videos

Last Updated: Jun 28, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

Area of Science:

  • Infectious Diseases
  • Surgical Pathology
  • Microbiology

Background:

  • The rise in antibiotic use and immunocompromised populations has led to increased Clostridium difficile infections (CDI).
  • CDI, once rare, now presents a growing challenge in surgical settings.
  • Understanding CDI's evolving epidemiology is crucial for healthcare professionals.

Observation:

  • This study provides a comprehensive overview of Clostridium difficile-induced conditions.
  • It examines the pathogenesis, diagnostic methods, and therapeutic strategies for CDI.
  • The increasing prevalence necessitates greater awareness among surgeons.

Findings:

  • Clostridium difficile infection presents complex challenges in pathogenesis and clinical management.
  • Accurate diagnostics and effective treatment protocols are essential for patient outcomes.
  • Surgeons must be prepared for the rising incidence of CDI in their practice.

Implications:

  • Enhanced understanding of CDI pathogenesis can lead to improved diagnostic tools.
  • Optimized treatment strategies are needed to combat antibiotic resistance associated with CDI.
  • Surgical professionals require updated knowledge to effectively manage Clostridium difficile infections.