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Updated: Jun 28, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Assessment and treatment of stroke in children
1Lori C. Jordan, MD Johns Hopkins University School of Medicine, 200 North Wolfe Street, Suite 2158,Baltimore, MD 21287, USA. ljordan2@jhmi.edu.
Insights
Pediatric stroke is a significant cause of childhood disability, affecting 2-3 per 100,000 children. Urgent evaluation and targeted treatment are crucial for improving outcomes in pediatric stroke patients.
Area of Science:
- Neurology
- Pediatrics
- Public Health
Background:
- Pediatric stroke is underrecognized despite being a major cause of childhood disability.
- Ischemic and hemorrhagic strokes occur with similar frequency in children.
- Limited research exists on evaluating and treating pediatric stroke, except in sickle cell disease.
Purpose of the Study:
- To highlight the significance of pediatric stroke as a cause of disability.
- To emphasize the need for urgent and thorough evaluation of children with stroke.
- To discuss current understanding and gaps in treatment guidelines for pediatric stroke.
Main Methods:
- Review of existing literature on pediatric stroke.
- Analysis of incidence and types of stroke in children.
- Comparison with adult stroke management and guidelines.
Main Results:
- Pediatric stroke incidence is 2-3 per 100,000 children.
- Ischemic and hemorrhagic strokes are equally common.
- Consensus guidelines exist for ischemic stroke but not hemorrhagic stroke in children.
Conclusions:
- Pediatric stroke requires increased awareness among physicians and families.
- Urgent, comprehensive evaluation is necessary to identify multiple risk factors.
- Treatment involves supportive care and targeted therapies based on stroke cause and patient factors.
Abstract:
Pediatric stroke remains underrecognized by physicians and families despite efforts to increase awareness. Although the incidence is only 2 to 3 per 100,000 children, stroke is a significant cause of disability in childhood. Ischemic and hemorrhagic strokes occur with approximately equal frequency. How these children should be evaluated and treated has not been well studied, except for randomized, controlled trials performed in children with sickle cell disease. There are consensus guidelines for the evaluation and treatment of ischemic stroke in children but not for hemorrhagic stroke. Extrapolation from the adult stroke literature is problematic in some cases. Children should be evaluated urgently and thoroughly, as multiple stroke risk factors may be present. Treatment includes supportive care geared to reducing metabolic demands in the setting of cerebral ischemia or hemorrhage, as well as targeted therapy depending on the presumed cause of stroke and individual patient risk factors.
Related Concept Videos
Stroke: Introduction and Types
Ischemic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction
Ischemic Stroke l: Introduction

