[Autoimmune haemolytic anaemia - as a mask of acute erythroleukaemia]

Erythroleukaemia (DI Guglielmo Desease) is a rare form of acute myeloid leukaemia. This pathology is extremely difficult to be diagnosed on the early stage. Acute erythroleukaemia may make its debut under the mask of haemolytic anaemia and can be acceptably suspected only after emergence of malignant cells in peripheral blood. In the paper is presented a case of 13 years old girl, who on the basis of anamnesis, clinical, and paraclinical data was diagnosed as having Autoimmune Haemolytic Anemia. As a result of prednisolone therapy full clinical and partial laboratory remission was achieved. A week later after stopping the treatment the patient was repeatedly hospitalized in very a bad condition, with blast cells in the peripheral blood (80% in bone marrow). According to morphological, cytochemical, immunological tests and cytogenetic analysis she was diagnosed as having Acute Erythroleukaemia.