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Updated: Jun 28, 2026
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
In vivo studies of a platinum(II) metallointercalator
Dianne M Fisher1, Ronald R Fenton, Janice R Aldrich-Wright
1School of Chemistry, The University of Sydney, NSW 2006, Australia.
Chemical Communications (Cambridge, England)
|November 11, 2008
Abstract:
An in vivo study for determining the toxicity and efficacy of [Pt(S,S-dach)(phen)Cl(2).1.5H(2)O.0.5HCl (PHENSS) in female Specific Pathogen Free (SPF) Swiss nude mice bearing PC3 tumour xenografts revealed PHENSS to be non-toxic and effective in decreasing tumour growth.
