Improving classification performance with discretization on biomedical datasets
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Updated: Jun 28, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
Jonathan L Lustgarten1, Vanathi Gopalakrishnan, Himanshu Grover
1Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.
Abstract:
Discretization acts as a variable selection method in addition to transforming the continuous values of the variable to discrete ones. Machine learning algorithms such as Support Vector Machines and Random Forests have been used for classification in high-dimensional genomic and proteomic data due to their robustness to the dimensionality of the data. We show that discretization can help improve significantly the classification performance of these algorithms as well as algorithms like Naïve Bayes that are sensitive to the dimensionality of the data.
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