Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 28, 2026

Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain
09:42

Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain

Published on: August 4, 2021

Lagged cells in alert monkey lateral geniculate nucleus.

Alan B Saul1

  • 1Department of Ophthalmology, Medical College of Georgia, Augusta, Georgia 30912, USA. asaul@mcg.edu

Visual Neuroscience
|November 13, 2008
PubMed
Summary

Lagged cells, crucial for visual processing, were identified in awake macaque monkeys for the first time. This finding in the lateral geniculate nucleus reveals diverse response timings, aiding cortical direction selectivity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacological Inhibition of Spermine Oxidase Reduces Neurodegeneration and Improves Retinal Function in Diabetic Mice.

Journal of clinical medicine·2020
Same author

Multifocal Electroretinography in the Presence of Temporal and Spatial Correlations and Eye Movements.

Vision (Basel, Switzerland)·2019
Same author

Detailed electroretinographic findings in rd8 mice.

Documenta ophthalmologica. Advances in ophthalmology·2017
Same author

Effects of fixational saccades on response timing in macaque lateral geniculate nucleus.

Visual neuroscience·2010
Same author

Lagged cells.

Neuro-Signals·2008
Same author

Temporal receptive field estimation using wavelets.

Journal of neuroscience methods·2008

Area of Science:

  • Neuroscience
  • Visual Processing
  • Primate Neurophysiology

Background:

  • Lagged cells, previously studied only in anesthetized cats, play a role in visual information processing.
  • Understanding their function in awake animals is critical for comprehending visual perception.

Purpose of the Study:

  • To investigate the presence and characteristics of lagged cells in the lateral geniculate nucleus of an awake, behaving macaque monkey.
  • To compare findings with previous studies in anesthetized animals.

Main Methods:

  • Extracellular recordings were performed in the lateral geniculate nucleus of an awake macaque monkey.
  • Identification of lagged cells based on their electrophysiological properties.

Main Results:

More Related Videos

Viral Tracing of Genetically Defined Neural Circuitry
13:06

Viral Tracing of Genetically Defined Neural Circuitry

Published on: October 17, 2012

Related Experiment Videos

Last Updated: Jun 28, 2026

Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain
09:42

Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain

Published on: August 4, 2021

Viral Tracing of Genetically Defined Neural Circuitry
13:06

Viral Tracing of Genetically Defined Neural Circuitry

Published on: October 17, 2012

  • Five lagged cells were successfully identified in the awake macaque.
  • Both parvocellular and magnocellular types of lagged cells were observed.
  • A continuous distribution of response timings and both sustained and transient responses in magnocellular cells were noted.

Conclusions:

  • The presence of lagged cells in awake primates confirms their role beyond anesthetized preparations.
  • The observed diversity in response timing suggests a sophisticated mechanism for visual signal processing.
  • These findings indicate that the cortex receives a wide range of timing information, potentially mediating multidimensional direction selectivity.