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Updated: Jun 28, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Botulinum toxin type A--treatment of a patient with multiple cutaneous piloleiomyomas
Maria K Sifaki1, Sabine Krueger-Krasagakis, Anastasios Koutsopoulos
1Department of Dermatology, Faculty of Medicine, University of Crete, Heraklion, Greece.
Background:
Treatment of multiple cutaneous piloleiomyomas which are rare, frequently painful, benign tumors originating from the arrector pilorum muscle of hair follicles is difficult.
Objective:
To determine the efficiency of botulinum toxin type A (BT-A) treatment for pain relief of cutaneous piloleiomyomas.
Methods:
A patient with multiple painful piloleiomyomas was treated with local injections of 200 units of BT-A.
Results:
There was a rapid and sustained decrease in pain. Treatment was repeated every 3 months for 2 years with the same efficacy.
Conclusion:
BT-A may be a promising new treatment option for multiple painful cutaneous piloleiomyomas.
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