Related Experiment Video
Updated: Jun 28, 2026

Establishing a Device for Sleep Deprivation in Mice
Published on: September 22, 2023
The effect of 60-h sleep deprivation on cardiovascular regulation and body temperature
Jani Vaara1, Heikki Kyröläinen, Mikko Koivu
1Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland. jani.vaara@sport.jyu.fi
Abstract:
This study examined cardiovascular regulation and body temperature (BT) during 60 h of sleep deprivation in 20 young healthy cadets. Heart rate variability was measured during an active orthostatic test (AOT). Measurements were performed each day in the morning and evening after 2, 14, 26, 38, 50 and 60 h of sleep deprivation. In AOT, in the sitting and standing positions, heart rate decreased (P < 0.001), while high frequency and low frequency power increased (P < 0.05-0.001) during sleep deprivation. Body temperature also decreased (P < 0.001), but no changes were detected in blood pressure. In conclusion, the accumulation of 60 h of sleep loss resulted in increased vagal outflow, as evidenced by decreased heart rate. In addition, BT decreased during sleep deprivation. Thus, sleep deprivation causes alterations in autonomic regulation of the heart, and in thermoregulation.
Related Concept Videos
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Factors Affecting Body Temperature
Factors may include:
Circadian Rhythms and Gene Regulation
Homeostatic Imbalances in Body Temperature
Decreased Body Temperature
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...

