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Published on: January 7, 2018
Stiff-person syndrome first manifesting in pregnancy
Denis Cerimagic1, Ervina Bilic
1Department of Neurology, Dubrovnik General Hospital, Dubrovnik, Croatia. deniscerimagic@yahoo.com
Abstract:
Stiff-person syndrome (SPS) is a rare neurological disorder characterised by progressive stiffness and painful muscle spasms. We present a case of the autoimmune form of glutamate decarboxylase-positive SPS that initially manifested in pregnancy. The diagnosis was made based on clinical, laboratory and electromyoneurographic criteria. The patient was administered low doses of diazepam and baclofen. Considering the clinical picture of SPS patients, caesarean section is the method of choice for pregnancy termination.
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