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Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
Published on: January 6, 2023
Adalimumab-induced acute myelogenic leukemia
Nakhle S Saba1, Semaan G Kosseifi, Edris A Charaf
1Division of Hematology/Oncology, Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, James H. Quillen VA Medical Center, TN 37684, USA.
Abstract:
Newer biological treatment strategies have been developed in the last decade with some promising outcomes. Their safety, however, has been questioned lately with multiple reports of increased risk for malignancies and infectious complications. These reports render their use suboptimal. We report a 44-year-old woman receiving adalimumab (Humira) for advanced juvenile rheumatoid arthritis who then developed acute myelogenic leukemia.