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Total organic carbon measurement as a substitute for the USP oxidizable substances test
G A Crane1, M W Mittleman, M Stephan
1Rosemount Analytical, Inc., Dohrmann Division, Santa Clara, California.
Journal of Parenteral Science and Technology : a Publication of the Parenteral Drug Association
|January 1, 1991
Abstract:
The insensitivity and variability of response of the USP Oxidizable Substances Test for waters are investigated. Instrumental measurement of Total Organic Carbon (TOC) is described, and the method is compared with the Oxidizable Substances Test. Pharmaceutical factory measurements of TOC in various water systems are discussed.