Related Experiment Video
Updated: Jun 27, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
Published on: January 18, 2018
[Ropivacaine infiltration during breast cancer surgery: postoperative acute and chronic pain effect]
G Baudry1, A Steghens, D Laplaza
1Pôle d'anesthésie-réanimation chirurgicale, centre hospitalier universitaire Jean-Minjoz, université de Franche-Comté, 3, boulevard Alexander-Fleming, 25000 Besançon, France. gerald.baudry@wanadoo.fr
Objectives:
Decrease acute pain after breast cancer surgery by an infiltration of ropivacaine. Analyse effect on chronic pain.
Study Design:
Prospective randomised double blind versus placebo study.
Patients And Methods:
Eighty-one patients randomised between two groups received wound infiltration with 40 ml of ropivacaine 4.75 mg/ml or placebo. Acute pain was assessed during 24h with analogical visual scale and antalgic consumption. One year later, telephonic interviews looked for chronic pain and evaluate it with McGill Pain Questionnaire.
Results:
Analogical visual scale pain score, antalgic consumption and chronic pain incidence were similar between groups.
Conclusion:
Ropivacaine scar infiltration provided no acute or chronic pain relief after breast cancer surgery.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Parenteral Anesthetics: Overview
