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Organ and tissue safety workshop 2007: advances and challenges
Jay A Fishman1, D Michael Strong, Matthew J Kuehnert
1Transplant Infectious Disease Program, Massachusetts General Hospital, 55 Fruit Street, GRJ 504, Boston, MA 02114, USA. jfishman@partners.org
Cell and Tissue Banking
|November 20, 2008
Summary
Preventing infection from organ and tissue transplants remains a challenge. Enhanced communication and integrated systems are crucial for improving allograft safety and preventing disease transmission.
Area of Science:
- Public Health
- Transplantation Medicine
- Infectious Disease
Background:
- The US identified critical gaps in organ and tissue allograft safety following a 2005 workshop.
- Subsequent workshops assessed progress and highlighted ongoing challenges in preventing allograft-associated disease transmission.
Framework:
- Development of the Transplantation Transmission Sentinel Network to improve communication.
- Focus on patient safety initiatives, including adverse event reporting and advanced microbiologic screening.
Implementation:
- Initiatives aimed at enhancing organ and tissue safety have been developed and assessed.
- Increased awareness of allograft-associated disease transmission challenges among stakeholders.
Implications:
- Continued progress requires systems integration across organ procurement organizations, tissue banks, and transplant infectious disease experts.
- Sustained commitment of resources and coordinated efforts are essential for developing tools to improve allograft recipient safety.
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