Related Experiment Video
Updated: Jun 27, 2026
07:30
Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Predicting ischaemic stroke subtype from presenting systolic blood pressure: the BASIC Project
W J Meurer1, B N Sánchez, M A Smith
1Stroke Program, University of Michigan Health System, USA.
Journal of Internal Medicine
|November 21, 2008
Summary
Low systolic blood pressure (SBP) at presentation is linked to cardioembolic stroke, a type of ischemic stroke. Increased suspicion for this stroke subtype is warranted in patients with lower SBP.
Area of Science:
- Neurology
- Cardiology
- Epidemiology
Background:
- Ischemic stroke subtypes have varying etiologies and risk factors.
- Understanding predictors of specific stroke subtypes is crucial for targeted prevention and treatment.
- Systolic blood pressure (SBP) is a key cardiovascular risk factor, but its association with stroke etiology requires further elucidation.
Purpose of the Study:
- To test the hypothesis that low presenting systolic blood pressure (SBP) predicts a cardioembolic stroke etiology.
- To investigate the association between presenting SBP and ischemic stroke subtypes.
Main Methods:
- A population-based study (Brain Attack Surveillance in Corpus Christi - BASIC) identified ischemic stroke cases.
- Multinomial logistic regression analyzed the relationship between stroke subtype and initial SBP.
- Data included 308 ischemic stroke cases with determined etiology between 2000-2002.
Main Results:
- Lower presenting SBP was significantly associated with stroke subtype (P = 0.001).
- Each 10 mmHg decrease in SBP increased the odds of cardioembolic stroke versus small vessel occlusion by 20%.
- Older age was also associated with an increased odds of cardioembolic stroke.
Conclusions:
- Lower initial SBP and older age are associated with cardioembolic stroke.
- Clinicians should consider cardioembolic stroke in patients presenting with low SBP.
- These findings aid in identifying stroke etiology and guiding clinical suspicion.
Related Concept Videos
01:29Stroke: Introduction and Types
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
01:10Pre-Procedural Guidelines for Assessing Blood Pressure
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:23Assessment of blood pressure in brachial artery(two-step method)
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
01:19Assessing Blood pressure using a doppler ultrasound
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment: