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Peroxynitrite-mediated lipid oxidation and nitration: mechanisms and consequences

Homero Rubbo1, Andrés Trostchansky, Valerie B O'Donnell

  • 1Departamento de Bioquímica and Center for Free Radical and Biomedical Research, Facultad de Medicina, Universidad de la República, Montevideo 11800, Uruguay. hrubbo@fmed.edu.uy

Archives of Biochemistry and Biophysics
|November 22, 2008
PubMed
Summary

Peroxynitrite causes lipid oxidation and nitration, creating new signaling molecules. These molecules modulate key lipid-metabolizing enzymes, offering insights into inflammatory processes.

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