Automatic summarization of MEDLINE citations for evidence-based medical treatment: a topic-oriented evaluation

Marcelo Fiszman1, Dina Demner-Fushman, Halil Kilicoglu

  • 1National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bldg 38A, Rm B1N-28J, Bethesda, MD 20894, USA. fiszmanm@mail.nih.gov

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Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
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Cancer Survival Analysis

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Targets for Drug Action: Overview01:26

Targets for Drug Action: Overview

Drugs target macromolecules to modify ongoing cellular processes. Primary drug targets include receptors, ion channels, transporters, and enzymes.
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Hazard Ratio01:12

Hazard Ratio

The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial evaluating a...
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Targeted Cancer Therapies

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There are several types of targeted therapies against specific...