Recurrent ameloblastoma following osseous reconstruction--a review of twenty years
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Updated: Jun 27, 2026

Techniques of Endoscopic Ossiculoplasty
Published on: January 26, 2024
André M Eckardt1, Horst Kokemüller, Peter Flemming
1Department of Oral and Maxillofacial Surgery (Head: Prof. Dr. Dr. N.-C. Gellrich), Hannover Medical School, Hannover, Germany. eckardt.andre@mh-hannover.de
Background:
The adequate therapy of ameloblastoma may require a compromise between the least destructive treatment possible of a benign tumour and a sufficiently radical method to prevent recurrences. Frequently recurrences appear after 10 years or longer, therefore regular follow-up visits even after more than 5 years are recommended. The primary reconstruction of bones and/or soft tissues, which is likely to be performed especially for benign processes is threatened by recurrences.
Methods:
A retrospective analysis of our patient group during the past 20 years has shown that a differentiated pretherapeutic securing of the histology as well as a radical surgical policy are the most important criteria, influencing the likelihood of recurrences. Three representative case histories are described below.
Results:
The rate of cumulative relapses with regard to various observation time amounted to 17% after 5 years and 19% after 10 years, respectively.
Conclusion:
Ameloblastomas carry a certain risk of developing local recurrences depending on histology and the type of surgical treatment. Long-term follow-up should be arranged.
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