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Updated: Jun 27, 2026

Ultrastructural Expansion Microscopy in Three In Vitro Life Cycle Stages of Trypanosoma cruzi

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Published on: May 12, 2023

Ultrastructural characteristics of chemodectomas.

G G Zelenov¹, A I Shchegolev, E G Kolokol'chikova

¹Department of Pathological Anatomy, A. V. Vishnevskii Institute of Surgery, Federal Agency for High-Technology Medical Care, Moscow.

Bulletin of Experimental Biology and Medicine

|November 26, 2008

Summary

This summary is machine-generated.

This study reveals distinct ultrastructural characteristics and cellular activity in chemodectoma tumors. Electron radioautography identified differences in protein synthesis and proliferation between light and dark cells.

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Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

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Published on: October 20, 2019

Area of Science:

Pathology
Oncology
Cell Biology

Background:

Chemodectomas are rare neuroendocrine tumors arising from paraganglia.
Understanding the cellular heterogeneity of these tumors is crucial for diagnosis and treatment.

Purpose of the Study:

To investigate the morphological and ultrastructural features of chemodectoma cells.
To analyze the protein-synthesizing and proliferative activity within different cell types of chemodectomas.

Main Methods:

Surgical resection of chemodectoma samples.
Electron microscopy for ultrastructural analysis.
Electron radioautography to assess cellular activity.

Main Results:

Demonstration of specific ultrastructural differences between light and dark cells in chemodectomas.
Differential protein synthesis rates observed between light and dark cell populations.
Variations in proliferative activity identified in light and dark cells.

Conclusions:

Chemodectomas exhibit cellular heterogeneity with distinct ultrastructural and functional properties.
Electron radioautography is a valuable tool for elucidating the activity of different cell types in neuroendocrine tumors.
These findings contribute to a deeper understanding of chemodectoma biology.